Dovitinib lactate hydrate

• Catalog Number: orb1300733
• Category: Small Molecules
• Description: Dovitinib lactate hydrate
• CAS Number: 915769-50-5
• Purity: 99.17%
• MW: 482.51
• SMILES: O.CC(O)C(O)=O.CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O
• Formula: C₂₄H₂₉FN₆O₅
• Biological Activity: Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.