DM1-SMe

• Catalog Number: orb1705074
• Category: Small Molecules
• Description: DM1-SMe
• CAS Number: 138148-68-2
• Purity: 98%
• MW: 784.38
• SMILES: C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCSSC)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]
• Formula: C₃₆H₅₀ClN₃O₁₀S₂
• Biological Activity: DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.