DM1-SMe

• Catalog Number: orb1705074
• Category: Small Molecules
• Description: DM1-SMe
• CAS Number: 138148-68-2
• Purity: 98%
• MW: 784.38
• SMILES: [H][C@@]12O[C@@]1(C)[C@H](CC(=O)N(C)c1cc(C\C(C)=C/C=C\[C@@H](OC)[C@@]3(O)C[C@]([H])(OC(=O)N3)[C@H]2C)cc(OC)c1Cl)OC(=O)[C@H](C)N(C)C(=O)CCSSC
• Formula: C₃₆H₅₀ClN₃O₁₀S₂
• Biological Activity: DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.