Didesmethylrocaglamide

• Catalog Number: orb1693474
• Category: Small Molecules
• Description: Didesmethylrocaglamide
• CAS Number: 177262-30-5
• Purity: 98%
• MW: 477.51
• SMILES: O[C@]12[C@]([C@@H]([C@@H](C(N)=O)[C@H]1O)C3=CC=CC=C3)(OC=4C2=C(OC)C=C(OC)C4)C5=CC=C(OC)C=C5
• Formula: C₂₇H₂₇NO₇
• Biological Activity: Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects, with an IC50 of 5 nM. It hinders several growth-promoting signaling pathways and triggers apoptosis in tumor cells, demonstrating antitumor activity[1].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.