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    Dideoxy-amanitin

    Dideoxy-amanitin

    Catalog Number: orb1982743

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    Catalog Numberorb1982743
    CategorySmall Molecules
    DescriptionDideoxy-amanitin
    CAS Number58255-46-2
    MW886.97
    SMILES[H][C@@]12C[C@@H](O)CN1C(=O)[C@H](CC(N)=O)NC(=O)[C@]1([H])CSc3[nH]c4ccccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1
    FormulaC39H54N10O12S
    Biological ActivityDideoxy-amanitin (compound 2), a derivative of α-Amanitin, functions as a potent, selective allosteric inhibitor of RNA polymerase II, demonstrating an inhibition concentration (IC50) of 74.2 nM [1].
    NoteFor research use only
    Expiration Date12 months from date of receipt.
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