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Catalog Number | orb1982743 |
---|---|
Category | Small Molecules |
Description | Dideoxy-amanitin |
CAS Number | 58255-46-2 |
MW | 886.97 |
SMILES | [H][C@@]12C[C@@H](O)CN1C(=O)[C@H](CC(N)=O)NC(=O)[C@]1([H])CSc3[nH]c4ccccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1 |
Formula | C39H54N10O12S |
Biological Activity | Dideoxy-amanitin (compound 2), a derivative of α-Amanitin, functions as a potent, selective allosteric inhibitor of RNA polymerase II, demonstrating an inhibition concentration (IC50) of 74.2 nM [1]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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