Dicumarol

• Catalog Number: orb1089660
• Category: Small Molecules
• Description: Dicoumarol (INN) or dicumarol (USAN) is a naturally occurring anticoagulant that functions as a functional vitamin K depleter (similar to warfarin, a drug that dicoumarol inspired). It is also used in biochemical experiments as an inhibitor of reductases. Like all 4-hydroxycoumarin drugs it is a competitive inhibitor of vitamin K epoxide reductase, an enzyme that recycles vitamin K, thus causing depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes. These compounds are not antagonists of Vitamin K directly—as they are in pharmaceutical uses—but rather promote depletion of vitamin K in bodily tissues allowing vitamin K's mechanism of action as a potent medication for dicoumarol toxicity. The mechanism of action of Vitamin K along with the toxicity of dicoumarol are measured with the prothrombin time (PT) blood test. (Source: https://en.wikipedia.org/wiki/Dicoumarol).
• CAS Number: [66-76-2]
• MW: 336.2949858
• SMILES: C1C=CC2C(=C(CC3C(=O)OC4C=CC=CC=4C=3O)C(OC=2C=1)=O)O
• Formula: C₁₉H₁₂O₆
• Note: For research use only
• Expiration Date: 12 months from date of receipt.