Desmorpholinyl Quizartinib-PEG2-COOH

• Catalog Number: orb1691031
• Category: Small Molecules
• Description: Desmorpholinyl Quizartinib-PEG2-COOH
• CAS Number: 2292116-14-2
• Purity: 98%
• MW: 607.68
• SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(OCCOCCOCCC(O)=O)ccc32)no1
• Formula: C₃₀H₃₃N₅O₇S
• Biological Activity: Desmorpholinyl Quizartinib-PEG2-COOH incorporates a ligand for FLT-3, and a PEG-based PROTAC linker. Desmorpholinyl Quizartinib-PEG2-COOH can be used in the synthesis of PROTAC FLT-3 degrader 1 (HY-114323). PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC 50 0.6 nM.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.