Dersimelagon

• Catalog Number: orb1702360
• Category: Small Molecules
• Description: Dersimelagon
• CAS Number: 1835256-48-8
• Purity: 97.35%
• MW: 675.75
• SMILES: C(=O)([C@@]1(F)[C@@H](CN(C1)C2CCCC2)C3=CC=C(OC)C=C3)N4C[C@@H]([C@@H](COC)C4)C5=C(C=C(C(F)(F)F)C=C5)N6CCC(C(O)=O)CC6
• Formula: C₃₆H₄₅F₄N₃O₅
• Biological Activity: Dersimelagon (MT-7117) is an orally active, selective agonist for the melanocortin 1 receptor (MC1R), demonstrating EC50 values of 8.16 nM (h), 3.91 nM (cm), 1.14 nM (m), and 0.251 nM (r) across species such as human, cynomolgus monkey, mouse, and rat, respectively. It exhibits strong affinity for human MC1R and MC4R, with Ki values of 2.26 nM and 32.9 nM, respectively. This compound is applied in the study of skin pigmentation.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.