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Catalog Number | orb1298145 |
---|---|
Category | Small Molecules |
Description | dCBP-1 |
CAS Number | 2484739-25-3 |
Purity | 98% |
MW | 1028.11 |
SMILES | CNC(N(CC1)Cc2c1n(C(CC1)CCN1C(CCOCCOCCOCCOCCNc(cc1)cc(C(N3C(CCC(N4)=O)C4=O)=O)c1C3=O)=O)nc2N(CCCc1c2)c1cc(C(F)F)c2-c1cn(C)nc1)=O |
Formula | C51H63F2N11O10 |
Biological Activity | dCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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