dCBP-1

• Catalog Number: orb1146577
• Category: Small Molecules
• Description: dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is exceptionally potent at killing multiple myeloma cells and can abolish the enhancer that drives MYC oncogene expression. As an efficient degrader of this unique class of acetyltransferases, dCBP-1 is a useful tool alongside domain inhibitors for dissecting the mechanism by which these factors coordinate enhancer activity in normal and diseased cells.
• CAS Number: [2484739-25-3]
• MW: 1027.4727
• SMILES: O=C(N1CCC(N(C2CCN(C(CCOCCOCCOCCOCCNC3=CC4=C(C(N(C(CC5)C(NC5=O)=O)C4=O)=O)C=C3)=O)CC2)N=C6N7CCCC8=C7C=C(C(F)F)C(C9=CN(C)N=C9)=C8)=C6C1)NC
• Formula: C₅₁H₆₃F₂N₁₁O₁₀
• Hazard Information: Non-Toxic
• Note: For research use only
• Expiration Date: 12 months from date of receipt.