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Catalog Number | orb1300262 |
---|---|
Category | Small Molecules |
Description | Dauricine |
CAS Number | 524-17-4 |
Purity | 99.38% |
MW | 624.77 |
SMILES | COc1cc2CCN(C)C(Cc3ccc(Oc4cc(CC5N(C)CCc6cc(OC)c(OC)cc56)ccc4O)cc3)c2cc1OC |
Formula | C38H44N2O6 |
Biological Activity | 1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profile of its downstream genes. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |