Dasatinib monohydrate

Catalog Number: orb1308590

Catalog Number	orb1308590
Category	Small Molecules
Description	Dasatinib monohydrate
CAS Number	863127-77-9
Purity	99.89%
MW	506.03
SMILES	n1cc(sc1Nc1nc(nc(N2CCN(CC2)CCO)c1)C)C(=O)Nc1c(cccc1C)Cl.O
Formula	C₂₂H₂₈ClN₇O₃S
Biological Activity	Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.
Storage	-20°C
Note	For research use only
Expiration Date	12 months from date of receipt.

Item 1 of 1
Dasatinib monohydrate [orb154614]
CAS Number:
[863127-77-9]
MW:
506.02
Formula:
C₂₂H₂₈ClN₇O₃S
Sizes Available: 1 g, 100 mg, 250 mg, 1 ml x 10 mm (in DMSO)
Dasatinib Monohydrate [orb609285]
Purity:
≥98%
CAS Number:
863127-77-9
MW:
506.02
Formula:
C₂₂H₂₆ClN₇O₂S H₂O
Sizes Available: 10 mg, 25 mg, 500 mg, 100 mg
Dasatinib Monohydrate [orb1891579]
CAS Number:
863127-77-9
Sizes Available: 500 mg
Dasatinib Monohydrate [orb1891580]
CAS Number:
863127-77-9
Sizes Available: 1000 mg