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    Dasatinib monohydrate

    Dasatinib monohydrate

    Catalog Number: orb1308590

    DispatchUsually dispatched within 3-5 working days
    $ 223.00
    Catalog Numberorb1308590
    CategorySmall Molecules
    DescriptionDasatinib monohydrate
    CAS Number863127-77-9
    Purity99.89%
    MW506.03
    SMILESn1cc(sc1Nc1nc(nc(N2CCN(CC2)CCO)c1)C)C(=O)Nc1c(cccc1C)Cl.O
    FormulaC22H28ClN7O3S
    Biological ActivityDasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.
    StorageStore at -20°C for 12 months.
    NoteFor research use only
    Expiration Date12 months from date of receipt.
    • Dasatinib monohydrate [orb154614]

      [863127-77-9]

      506.02

      C22H28ClN7O3S

      10 mM * 1 mL in DMSO, 1 g, 100 mg, 250 mg
    • Dasatinib Monohydrate [orb609285]

      ≥98%

      863127-77-9

      506.02

      C22H26ClN7O2S H2O

      10 mg, 500 mg, 100 mg, 25 mg
    • Dasatinib monohydrate [orb1223826]

      > 98%(HPLC)

      863127-77-9

      50 mg, 100 mg, 1 g, 500 mg, 200 mg
    • Dasatinib Monohydrate [orb1891579]

      863127-77-9

      500 mg
    • Dasatinib Monohydrate [orb1891580]

      863127-77-9

      1000 mg
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