Dasatinib hydrochloride

• Catalog Number: orb1704834
• Category: Small Molecules
• Description: Dasatinib hydrochloride
• CAS Number: 854001-07-3
• Purity: 99.98%
• MW: 524.47
• SMILES: Cl.O=C(NC=1C(Cl)=CC=CC1C)C=2SC(=NC2)NC=3N=C(N=C(C3)N4CCN(CCO)CC4)C
• Formula: C₂₂H₂₇Cl₂N₇O₂S
• Biological Activity: Dasatinib hydrochloride (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride hydrochloride inhibits Bcr-Abl and Src with IC50s of < 1.0 nM and 0.5 nM, respectively. Dasatinib hydrochloride hydrochloride also induces Apoptosis and Autophagy.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.