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| Catalog Number | orb181231 |
|---|---|
| Category | Small Molecules |
| Description | Darapladib is a selective and orally active inhibitor of Lp-PLA2 (IC50= 270 pM) |
| CAS Number | [356057-34-6] |
| MW | 666.77 |
| SMILES | FC1=CC=C(CSC(N(CC(N(CCN(CC)CC)CC2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)=O)C4=C5CCC4)=NC5=O)C=C1 |
| Formula | C36H38F4N4O2S |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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Morigny, Pauline et al. Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy J Cachexia Sarcopenia Muscle, (2021)
Applications
Cell Culture, In vivo
Reactivity
Mouse
Chemical structure of Darapladib
Darapladib-impurity [orb1741518]
0.9804
1389264-17-8
666.77
C36H38F4N4O2S
100 mg, 10 mg, 25 mg, 50 mg, 1 mg, 5 mg, 500 mgDarapladib [orb1301065]
99.85%
356057-34-6
666.77
C36H38F4N4O2S
2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 1 mg, 100 mg, 500 mg, 1 ml x 10 mm (in DMSO)
