DAPT

• Catalog Number: orb181230
• Category: Small Molecules
• Description: DAPT(GSI-IX) is an inhibitor of γ-secretase; DAPT causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma.
• CAS Number: [208255-80-5]
• MW: 432.4604
• SMILES: FC1C([H])=C(C([H])=C(C=1[H])C([H])([H])C(N([H])[C@@]([H])(C([H])([H])[H])C(N([H])[C@]([H])(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1C([H])=C([H])C([H])=C([H])C=1[H])=O)=O)F
• Formula: C₂₃H₂₆F₂N₂O₄
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of DAPT