DAPT

• Catalog Number: orb1300985
• Category: Small Molecules
• Description: DAPT
• CAS Number: 208255-80-5
• Purity: 99.81%
• MW: 432.46
• SMILES: C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@H](C(=O)OC(C)(C)C)c1ccccc1
• Formula: C₂₃H₂₆F₂N₂O₄
• Biological Activity: DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.