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Catalog Number | orb1300985 |
---|---|
Category | Small Molecules |
Description | DAPT |
CAS Number | 208255-80-5 |
Purity | 99.81% |
MW | 432.46 |
SMILES | [C@@H](NC([C@@H](NC(CC1=CC(F)=CC(F)=C1)=O)C)=O)(C(OC(C)(C)C)=O)C2=CC=CC=C2 |
Formula | C23H26F2N2O4 |
Biological Activity | DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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