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Catalog Number | orb1682848 |
---|---|
Category | Small Molecules |
Description | Danshenol A |
CAS Number | 189308-08-5 |
Purity | 98% |
MW | 336.38 |
SMILES | C[C@H]1COC2=C1C(=O)[C@](O)(CC(C)=O)c1c2ccc2c(C)cccc12 |
Formula | C21H20O4 |
Biological Activity | Danshenol A has strong aldose reductase (AR) inhibitory activity, has IC50 of 0.10 microM which is comparable to that of epalrestat in clinical use. Danshenol A also has antitumor activity in T-24, QGY, K562, Me180 and BIU87 cell lines, shows inhibited growth of K562 (IC50 = 0.53 μg/mL), T-24 (IC50 = 7.94 μg/mL), QGY (IC50 = 4.65 μg/mL) and Me180 (IC50 = 6.89 μg/mL) cell lines. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
336.387 | |
C21H20O4 |
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