Danicopan

• Catalog Number: orb1298871
• Category: Small Molecules
• Description: Danicopan
• CAS Number: 1903768-17-1
• Purity: 99.94%
• MW: 580.41
• SMILES: CC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(cc12)-c1cnc(C)nc1
• Formula: C₂₆H₂₃BrFN₇O₃
• Biological Activity: Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement pathway in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.