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Dactolisib hydrochloride

Dactolisib hydrochloride

Catalog Number: orb2814034

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Catalog Numberorb2814034
CategorySmall Molecules
DescriptionDactolisib (BEZ235) hydrochloride is an orally active dual inhibitor of pan-class I PI3K and mTOR, targeting p110α/γ/δ/β and mTOR, with IC50 values of 4 nM, 5 nM, 7 nM, 75 nM, and 20.7 nM, respectively. It inhibits both mTORC1 and mTORC2.
CAS Number2319647-83-9
MW506
SMILESCl.N#CC(C1=CC=C(C=C1)N2C(=O)N(C=3C=NC4=CC=C(C=C4C32)C=5C=NC6=CC=CC=C6C5)C)(C)C
FormulaC30H24ClN5O
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.