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Catalog Number | orb2814034 |
---|---|
Category | Small Molecules |
Description | Dactolisib (BEZ235) hydrochloride is an orally active dual inhibitor of pan-class I PI3K and mTOR, targeting p110α/γ/δ/β and mTOR, with IC50 values of 4 nM, 5 nM, 7 nM, 75 nM, and 20.7 nM, respectively. It inhibits both mTORC1 and mTORC2. |
CAS Number | 2319647-83-9 |
MW | 506 |
SMILES | Cl.N#CC(C1=CC=C(C=C1)N2C(=O)N(C=3C=NC4=CC=C(C=C4C32)C=5C=NC6=CC=CC=C6C5)C)(C)C |
Formula | C30H24ClN5O |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |