Dabrafenib

• Catalog Number: orb1307175
• Category: Small Molecules
• Description: Dabrafenib
• CAS Number: 1195765-45-7
• Purity: 99.83%
• MW: 519.56
• SMILES: FC1=C(C2=C(SC(C(C)(C)C)=N2)C3=NC(N)=NC=C3)C=CC=C1NS(=O)(=O)C4=C(F)C=CC=C4F
• Formula: C₂₃H₂₀F₃N₅O₂S₂
• Biological Activity: Dabrafenib (GSK2118436A) is a Raf inhibitor that inhibits C-Raf and B-RafV600E (IC50=5/0.6 nM) and is ATP-competitive. Dabrafenib exhibits antitumor activity for the treatment of B-RafV600E-mutated melanoma.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.