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Dabrafenib (GSK2118436)
Catalog Number: orb154735
| Catalog Number | orb154735 |
|---|---|
| Category | Small Molecules |
| Description | Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. Phase 3. |
| CAS Number | [1195765-45-7] |
| MW | 519.5624 |
| SMILES | S1C(C2C([H])=C([H])N=C(N([H])[H])N=2)=C(C2C([H])=C([H])C([H])=C(C=2F)N([H])S(C2C(=C([H])C([H])=C([H])C=2F)F)(=O)=O)N=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] |
| Formula | C23H20F3N5O2S2 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Chemical structure of Dabrafenib (GSK2118436)
