Cys-Pexiganan

• Catalog Number: orb1140514
• Category: Proteins
• Description: The broad-spectrum antibacterial pexiganan with an additional N-terminal cysteine; Antimicrobial peptides.
• Modifications: C terminal amide.
• Structure: H-Cys-Gly-Ile-Gly-Lys-Phe-Leu-Lys-Lys-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Lys-Ile-Leu-Lys-Lys-NH2
• Target Areas: Antibacterials
• Form/Appearance: Freeze dried solid
• Purity: > 95% by HPLC
• MW: 2580.35 Da
• Formula: C₁₂₅H₂₁₅N₃₃O₂₃S
• Solubility (25°C): Soluble in water
• Protein Sequence: H-Cys-Gly-Ile-Gly-Lys-Phe-Leu-Lys-Lys-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Lys-Ile-Leu-Lys-Lys-NH2
• Storage: Store dry, frozen and in the dark
• Alternative names: AM230, CGIGKFLKKAKKFGKAFVKILKK-NH2, Cys-Pexiganan,
• Background: Cys-Pexiganan is the broad-spectrum antibacterial pexiganan with an additional N-terminal cysteine attached. Pexiganan is a 22-amino acid analog of the naturally occurring antimicrobial magainin2, extracted from the skin of the African frog Xenopus laevis. Pexiganan exhibits in vitro broad-spectrum antibacterial activity against many clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria and is the best-studied AMP to date for therapeutic purposes. The addition of the N-terminal cysteine in Cys-pexiganan allows immobilization of pexiganan as a novel approach towards endowing material surfaces with bactericidal properties as well as attachment of fluorescent or biotin tags.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.