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Catalog Number | orb1308421 |
---|---|
Category | Small Molecules |
Description | CVT-10216 |
CAS Number | 1005334-57-5 |
Purity | 99.16% |
MW | 465.48 |
SMILES | O=C(O)C1=CC=CC(COC2=CC=C3C(C(C4=CC=C(NS(=O)(C)=O)C=C4)=COC3=C2)=O)=C1 |
Formula | C24H19NO7S |
Biological Activity | CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50: 29 nM). CVT-10216 also has inhibitory effect of ALDH-1 (IC50: 1.3 μM). CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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