Cucurbitacin IIA

• Catalog Number: orb1303390
• Category: Small Molecules
• Description: Cucurbitacin IIA
• CAS Number: 58546-34-2
• Purity: 99.87%
• MW: 562.73
• SMILES: [H][C@@]1([C@H](O)C[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(C[C@H](O)[C@@H](O)C4(C)C)[C@]3(C)C(=O)C[C@]12C)[C@@](C)(O)C(=O)CCC(C)(C)OC(C)=O
• Formula: C₃₂H₅₀O₈
• Biological Activity: 1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.