CU-CPT-9b

• Catalog Number: orb422464
• Category: Small Molecules
• Description: CU-CPT9a is an antagonist of toll-like receptor 8 (TLR8). It inhibits activation of NF-κB induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells (IC50 = 0.5 nM). CU-CPT9a reverses R-848-induced increases in NF-κB p65, IRAK-4, and TRAF3 protein levels in HEK-Blue cells.
• CAS Number: [2165340-32-7]
• MW: 265.31
• SMILES: C(C1=CC=NC2C=C(OC)C=CC1=2)1=CC=C(O)C(C)=C1
• Formula: C₁₇H₁₅NO₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.