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Catalog Number | orb1694658 |
---|---|
Category | Small Molecules |
Description | CU-CPD107 |
CAS Number | 2573912-32-8 |
Purity | 98.86% |
MW | 400.25 |
SMILES | C(C(C)(C)O)N1C(=C(I)N=C1COCC)C2=CC=CC=C2 |
Formula | C16H21IN2O2 |
Biological Activity | CU-CPD107 is a selective agonist of toll-like receptor 8 (TLR8) and also shows activation activity against ssRNA ligands. CU-CPD107 acts as an inhibitor of TLR8 signaling in the presence of R848 (IC50=13.7 μM). CU-CPD107 exhibited coagonist activity in the presence of ssRNA, while CU-CPD107 alone could not affect TLR8 signal transduction. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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