CT-1 Protein, Human, Recombinant (His)

• Catalog Number: orb1962130
• Category: Proteins
• Description: Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.
• Tag: N-6xHis
• Purity: 98.00%
• MW: 25 KDa (reducing condition)
• UniProt ID: Q16619
• Protein Sequence: Met1-Ala201
• Expression System: E. coli
• Biological Origin: Human
• Biological Activity: Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.
• Expression Region: Met1-Ala201
• Storage: -20°C
• Note: For research use only
• Expiration Date: 6 months from date of receipt.