You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1689903 |
---|---|
Category | Small Molecules |
Description | Cridanimod sodium |
CAS Number | 58880-43-6 |
Purity | 98% |
MW | 276.24 |
SMILES | [Na+].[O-]C(=O)CN1C2=C(C=CC=C2)C(=O)C2=C1C=CC=C2 |
Formula | C15H11NNaO3 |
Biological Activity | Cridanimod can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen released from the ovaries. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |