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Cridanimod sodium

Cridanimod sodium

Catalog Number: orb1689903

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Catalog Numberorb1689903
CategorySmall Molecules
DescriptionCridanimod sodium
CAS Number58880-43-6
Purity98%
MW276.24
SMILES[Na+].[O-]C(=O)CN1C2=C(C=CC=C2)C(=O)C2=C1C=CC=C2
FormulaC15H11NNaO3
Biological ActivityCridanimod can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen released from the ovaries.
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • Cridanimod sodium [orb573156]

    [58880-43-6]

    275.2346

    C15H10NO3-.NA+

    100 mg, 250 mg, 1 g