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Catalog Number | orb1305847 |
---|---|
Category | Small Molecules |
Description | CRANAD 2 |
CAS Number | 1193447-34-5 |
Purity | 98.53% |
MW | 410.27 |
SMILES | C(=C/C1=CC=C(N(C)C)C=C1)\C=2[CH-]C(/C=C/C3=CC=C(N(C)C)C=C3)=O[B+3]([F-])([F-])O2 |
Formula | C23H25BF2N2O2 |
Biological Activity | CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits. Upon interacting with Abeta aggregates, CRANAD-2 undergoes a range of changes, which include a 70-fold fluorescence intensity increase, a 90 nm blue shift (from 805 to 715 nm), and a large increase in quantum yield. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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