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Catalog Number | orb1982284 |
---|---|
Category | Small Molecules |
Description | CPD-1224, an orally active derivative that binds cereblon ligands to ALK inhibitors, specifically targets and degrades EML4-ALK oncogenic fusions, including ALK and its mutants L1196M/G1202R. |
CAS Number | 2891620-68-9 |
Purity | 98.00% |
MW | 855.4 |
SMILES | O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CC(C4)CN5CCC(C6=CC(OC)=C(C=C6C)NC7=NC=C(Cl)C(=N7)NC=8C=CC=CC8S(=O)(=O)C(C)C)CC5 |
Formula | C43H47ClN8O7S |
Biological Activity | CPD-1224, an orally active derivative that binds cereblon ligands to ALK inhibitors, specifically targets and degrades EML4-ALK oncogenic fusions, including ALK and its mutants L1196M/G1202R. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |