Conoidin A

• Catalog Number: orb1306237
• Category: Small Molecules
• Description: Conoidin A
• CAS Number: 18080-67-6
• Purity: 98.00%
• MW: 347.99
• SMILES: [O-][N+]1=C(CBr)C(CBr)=[N+]([O-])C2=C1C=CC=C2
• Formula: C₁₀H₈Br₂N₂O₂
• Biological Activity: Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. It also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII). Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.