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Compound 401
Catalog Number: orb146120
| Catalog Number | orb146120 |
|---|---|
| Category | Small Molecules |
| Description | Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over FRAP (mTOR) (IC50 = 5.3 μM). |
| CAS Number | [168425-64-7] |
| MW | 281.3092 |
| SMILES | O1C([H])([H])C([H])([H])N(C2=C([H])C(N3C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C4C3=N2)=O)C([H])([H])C1([H])[H] |
| Formula | C16H15N3O2 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Chemical structure of Compound 401
Compound 401 [orb1304029]
99.76%
168425-64-7
281.31
C16H15N3O2
200 mg, 1 ml x 10 mm (in DMSO), 100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 2 mg
