COH34

• Catalog Number: orb1309820
• Category: Small Molecules
• Description: COH34
• CAS Number: 906439-72-3
• Purity: 98%
• MW: 293.38
• SMILES: C(=NSC1=CC=C(C)C=C1)C=2C3=C(C=CC2O)C=CC=C3
• Formula: C₁₈H₁₅NOS
• Biological Activity: COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.