CNX-500

• Catalog Number: orb757557
• Category: Small Molecules
• Description: CNX-500 is a probe consisting of a covalent Btk inhibitor (CC-292) chemically linked to biotin. CNX-500 retains inhibitory activity against Btk (IC50 of 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase epidermal growth factor receptor, and upstream Src-family kinases including Syk and Lyn.
• CAS Number: [1202758-21-1]
• MW: 961.18
• SMILES: CC(C=N1)=C(NC2=CC(NC(C=C)=O)=CC=C2)N=C1NC3=CC=CC(OCCCNC(CCCC(NCCCOCCOCCOCCCNC(CCCC[C@H]4[C@@H](NC5=O)[C@@H](N5)CS4)=O)=O)=O)=C3
• Formula: C₄₈H₆₈N₁₀O₉S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.