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Catalog Number | orb1308447 |
---|---|
Category | Small Molecules |
Description | CITCO |
CAS Number | 338404-52-7 |
Purity | 99.62% |
MW | 436.74 |
SMILES | C(=NOCC1=CC(Cl)=C(Cl)C=C1)C2=C(N=C3N2C=CS3)C4=CC=C(Cl)C=C4 |
Formula | C19H12Cl3N3OS |
Biological Activity | CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it also is a selective Constitutive androstane receptor (CAR) agonist. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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