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Catalog Number | orb1942051 |
---|---|
Category | Small Molecules |
Description | Cisd2 agonist 2 |
CAS Number | 2916371-59-8 |
MW | 306.34 |
SMILES | O=C(OC)C1=C(SC(C(=O)NC2=CC=C(O)C=C2)=C1C)N |
Formula | C14H14N2O4S |
Biological Activity | Cisd2 agonist 2 (compound 6), with an EC50 of 191 nM, is an orally active activator of Cisd2, a protein whose levels are associated with nonalcoholic fatty liver disease (NAFLD). In vivo studies have demonstrated that Cisd2 agonist 2 exhibits no significant toxicity in heterozygous hepatocyte-specific Cisd2 knockout (Cisd2hKO-het) mice [1]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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