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Catalog Number | orb1308452 |
---|---|
Category | Small Molecules |
Description | Ciliobrevin D |
CAS Number | 1370554-01-0 |
Purity | 100% |
MW | 392.62 |
SMILES | C(C(=O)C1=C(Cl)C=C(Cl)C=C1)(C#N)=C2NC=3C(C(=O)N2)=CC=C(Cl)C3 |
Formula | C17H8Cl3N3O2 |
Biological Activity | Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity in vitro. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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