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CHIR-99021
Catalog Number: orb1305728
| Catalog Number | orb1305728 |
|---|---|
| Category | Small Molecules |
| Description | CHIR-99021 |
| CAS Number | 252917-06-9 |
| Purity | 98.63% |
| MW | 465.34 |
| SMILES | ClC1=C(C=2C(=CN=C(NCCNC3=CC=C(C#N)C=N3)N2)C=4NC(C)=CN4)C=CC(Cl)=C1 |
| Formula | C22H18Cl2N8 |
| Biological Activity | CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells. |
| Storage | Store at -20°C for 12 months. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 2
CHIR-99021 (CT99021) [orb154612]
[252917-06-9]
465.34
C22H18Cl2N8
10 mM * 1 mL in DMSO, 1 g, 100 mg, 250 mg - Item 1 of 1
CHIR-99021 monohydrochloride [orb1941068]
> 98% (HPLC)
1797989-42-4
1 g, 500 mg, 200 mg, 100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 2 mg
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