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Catalog Number | orb1300845 |
---|---|
Category | Small Molecules |
Description | CHIR-124 |
CAS Number | 405168-58-3 |
Purity | 98.35% |
MW | 419.91 |
SMILES | N(C1=C(C(=O)NC=2C1=CC(Cl)=CC2)C=3NC=4C(N3)=CC=CC4)[C@H]5C6CCN(C5)CC6 |
Formula | C23H22ClN5O |
Biological Activity | CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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