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Catalog Number | orb1702427 |
---|---|
Category | Small Molecules |
Description | CH5447240 |
CAS Number | 1253919-92-4 |
Purity | 98% |
MW | 517.68 |
SMILES | O=C1C2(NC(=N1)[C@H]3CC[C@H](C)CC3)CCN(S(CCC4=C(C)C=C(N(C(N)=O)C)C=C4C)(=O)=O)CC2 |
Formula | C26H39N5O4S |
Biological Activity | CH5447240 is an effective Human Parathyroid Hormone Receptor 1 (hPTHR1) Agonist for the treatment of Hypoparathyroidism. CH5447240 showed a potent in vitro hPTHR1 agonist effect (EC20: 3.0 nM; EC50: 12 nM). It showed 55% oral bioavailability and a significantly elevated serum calcium level in hypocalcemic model rats. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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