Cevidoplenib

• Catalog Number: orb746249
• Category: Small Molecules
• Description: Cevidoplenib, also known as SKIO703, is am orally active, potent and selective SYK inhibitor with potential anti-inflammatory and immunomodulating activities. Upon oral administration, cevidoplenib binds to and inhibits the activity of SYK, blocking Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, neutrophils, mast cells, natural killer (NK) cells and B cells. This leads to the inhibition of the activation of these inflammatory cells, and the related inflammatory responses and tissue damage.
• CAS Number: [1703788-21-9]
• MW: 473.537
• SMILES: C(C1CC1)(C1C2=C(N(C)C=1)C=CC(NC1=NC=CC(N3C=C(CN4C[C@H](O)CO4)C(C)=N3)=N1)=C2)=O
• Formula: C₂₅H₂₇N₇O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.