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Catalog Number | orb1679084 |
---|---|
Category | Small Molecules |
Description | Cenupatide |
CAS Number | 1006388-38-0 |
Purity | 98% |
MW | 617.756 |
SMILES | CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(C)(C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@](C)(Cc1ccccc1)C(N)=O |
Formula | C28H47N11O5 |
Biological Activity | Cenupatide is a urokinase plasminogen activator receptor (uPAR) inhibitor. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of STZ-induced diabetes. Cenupatide reverted STZ-induced up-regulation of uPA levels and activity, while uPAR on podocytes and (s)uPAR were unaffected. In glomeruli, Cenupatide inhibited FPR2 expression. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
97.62% | |
677.8 | |
C30H51N11O7 |