CDN1163

• Catalog Number: orb746381
• Category: Small Molecules
• Description: CDN1163 (CDN-1163) is a small molecule, allosteric activator of SERCA2, dose-dependently increases the Vmax of SERCA2 Ca2+-ATPase activity in ER microsomes; increases Ca2+-ATPase activity and significantly enhances Ca2+ uptake into the ER, attenuates H2O2-stimulated cell death in HEK cells; improves glucose homeostasis and metabolic parameters, increases glucose tolerance in ob/ob mice; CDN1163 reduces lipid accumulation and decreases lipogenesis in obese mice livers.
• CAS Number: [892711-75-0]
• MW: 320.392
• SMILES: C(NC1=C2C(=CC=C1)C=CC(C)=N2)(=O)C1=CC=C(OC(C)C)C=C1
• Formula: C₂₀H₂₀N₂O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.