CDKI-73

• Catalog Number: orb1308471
• Category: Small Molecules
• Description: CDKI-73
• CAS Number: 1421693-22-2
• Purity: 98.11%
• MW: 394.45
• SMILES: CC1=C(SC(NC)=N1)C2=NC(NC3=CC(S(N)(=O)=O)=CC=C3)=NC=C2F
• Formula: C₁₅H₁₅FN₆O₂S₂
• Biological Activity: CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effect of cisplatin.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.