CD86 Antibody (PE/Cy7)

• Catalog Number: orb1993551
• Category: Antibodies
• Description: CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
• Clonality: Monoclonal
• Clone Number: BU63
• Tested applications: FC
• Reactivity: Human
• Isotype: Mouse IgG1
• Immunogen: B-lymphoblastoid cell line ARH 77
• Conjugation: PE/Cy7
• Target: CD86
• Entrez: 942
• UniProt ID: P42081
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: B7-2, FUN-1, LAB72
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Expiration Date: 12 months from date of receipt.