CD39 Antibody (FITC)

• Catalog Number: orb1570910
• Category: Antibodies
• Description: CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), is a cell surface enzyme (with intracellular N- and C-terminus) which hydrolyzes extracellular ATP and ADP to AMP. Inhibition of its enzymatic activity may confer anticancer benefits. The formation of oligomers in the plasma membrane is essential for enzyme activity. It is expressed on Treg cells, and in other cell types, such as mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets. Hydrolysis of ATP and ADP inhibits inflammatory and thrombotic responses. In the nervous system, it regulates purinergic neurotransmission.
• Clonality: Monoclonal
• Clone Number: TU66
• Tested applications: FC
• Reactivity: Human
• Isotype: Mouse IgG2b kappa
• Conjugation: FITC
• Target: CD39
• Entrez: 953
• UniProt ID: P49961
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: ETDH1, LCAA, Ecto-ATPase 1, Ecto-apyrase, ENTPD1
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Expiration Date: 12 months from date of receipt.

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD39 (TU66) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).

Separation of human monocytes (red-filled) from CD39 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD39 (TU66) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).