CD38 Antibody (Pacific Orange)

• Catalog Number: orb1993642
• Category: Antibodies
• Description: CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration.
• Clonality: Monoclonal
• Clone Number: HIT2
• Tested applications: FC
• Reactivity: Human
• Isotype: Mouse IgG1
• Immunogen: Human thymocytes in foetus
• Conjugation: Pacific Orange
• Target: CD38
• Entrez: 952
• UniProt ID: P28907
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Alternative names: ADPRC1, cADPr hydrolase 1, T10, NAD(+) nucleosidas
• Note: For research use only
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
• Expiration Date: 12 months from date of receipt.