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Catalog Number | orb411568 |
---|---|
Category | Antibodies |
Description | Human monoclonal antibody to CD33 |
Species/Host | Human |
Clonality | Monoclonal |
Clone Number | hP67.6 (Gemtuzumab) |
Tested applications | FC, IF |
Reactivity | Human |
Isotype | IgG |
Immunogen | Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells. |
Concentration | 1 mg/ml |
Purity | Purified |
Conjugation | Unconjugated |
Target | CD33 |
UniProt ID | P20138 |
Storage | Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. |
Buffer/Preservatives | PBS with 0.02% Proclin 300. |
Alternative names | Siglec-3 Read more... |
Note | For research use only |
Application notes | A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence. |
Expiration Date | 12 months from date of receipt. |
ELISA, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
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