CD33 antibody

• Catalog Number: orb411567
• Category: Antibodies
• Description: Human monoclonal antibody to CD33
• Species/Host: Human
• Clonality: Monoclonal
• Clone Number: hP67.6 (Gemtuzumab)
• Tested applications: FC, IF
• Reactivity: Human
• Isotype: IgG4
• Immunogen: Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: CD33
• UniProt ID: P20138
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Siglec-3
• Note: For research use only
• Application notes: A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
• Expiration Date: 12 months from date of receipt.