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Catalog Number | orb1993548 |
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Category | Antibodies |
Description | CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. |
Clonality | Monoclonal |
Clone Number | CD28.2 |
Tested applications | FC |
Reactivity | Human, Primate |
Isotype | Mouse IgG1 kappa |
Immunogen | DC28.1.3.3 murine T cell hybridoma transfected with human CD28 cDNA |
Conjugation | PE/Cy7 |
Target | CD28 |
Entrez | 940 |
UniProt ID | P10747 |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Alternative names | TP44 Read more... |
Note | For research use only |
Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Expiration Date | 12 months from date of receipt. |
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