CD22 Biosimilar Antibody

• Catalog Number: orb1671891
• Category: Antibodies
• Description: CD22 Biosimilar Antibody
• Clonality: Recombinant
• Clone Number: hL22 (Epratuzumab)
• Tested applications: Blocking, FC, IP
• Reactivity: Human, Primate
• Isotype: IgG kappa
• Immunogen: This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells. Murine sequences comprise 5–10% of the molecule, with the remainder being human framework sequences, which greatly reduces the potential for immunogenicity (Traczewski, 2010).
• Concentration: batch dependent
• Conjugation: Unconjugated
• Target: CD22
• UniProt ID: P20273
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Leu14, B-cell receptor CD22, B-lymphocyte cell adh
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Flow-cytometry using anti-CD22 antibody Epratuzum28. Human lymphocytes were stained with an isotype control (3.0 - panel A) or the rmeric version of Eptratuzum2 - panel B) at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.

Flow-cytometry using anti-CD22 antibody Epratuzum28. Rhesus monkey lymphocytes were stained with an isotype control (3.0 - panel A) or the rmeric version of Epratuzum2 - panel B) at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.

Flow-cytometry using anti-CD22 antibody Epratuzum28. Cynomolgus monkey lymphocytes were stained with an isotype control (3.0 - panel A) or the rmeric version of Epratuzum2 - panel B at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.